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Cell & Molecular Biology · Problem type
What each checkpoint checks
Use this for “A cell at metaphase has one kinetochore not yet attached. Which checkpoint holds it, and before which step?”
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Which checkpoint checks it?
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Assumptions
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The G1/S checkpoint comes before the DNA is copied, G2/M before mitosis, and the spindle checkpoint before anaphase.
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p53 builds up when DNA is damaged and stops the cycle through p21, which blocks the CDKs.
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