SME
College · Engineering
Biotransport
4 topics
Bioengineering
Before this course
Topics
Diffusion in tissue
Blood flow
Mass transfer
Pharmacokinetics
Main lesson
Repeated doses and the steady state
Use this for “A 500 mg dose every 8 h, clearance 5 L/h. What is the average steady-state level?”
A constant infusion
Use this for “What infusion rate holds 10 mg/L when clearance is 5 L/h, and how long until the level is 90% of the way there?”
An oral dose: peak time and peak level
Use this for “A 500 mg tablet is absorbed at kₐ = 1 h⁻¹ into 50 L and cleared at k = 0.1 h⁻¹. When does the level peak, and how high?”
Course test
See what you know: 10 questions on this course
New questions each time. Pass to mark it complete.